吴士良 那彦群 金杰 薛兆英 郭应禄 吴士良 那彦群 金杰 薛兆英 郭应禄(100034 北京医科大学第一附属医院泌尿外科，北京医科大学泌尿外科研究所) 中华泌尿外科杂志 1999 0 20 1


    关键词：前列腺肿瘤；癌；雄激素全阻断；氟他胺 期刊 zhmnwkzz 0 论 著 fur -->


    

【摘要 】 目的 了解雄激素全阻断方法在前列腺癌治疗中的作用。 方法 睾丸切除加氟他胺治疗 C、 D 期前列腺癌患者 23例，并与单纯应用氟他胺治疗的 23例进行对照。 结果 雄激素全阻断疗法在降低 PSA 及缩小前列腺体积上优于对照组。有效率 (完全缓解率加部分缓解率 )治疗组为 65%，对照组为 39%。 结论 在前列腺癌的治疗中，雄激素全阻断治疗更合理，也更有效。

A comparison between maximal androgen blockade and simple retarder of androgen receptor in the treatment of proststic carcinoma

WU Shiliang,NA Yanqun,JIN Jie,et al.

    Institute of Urology,Beijing Medical University,Beijing 100034

【 Abstract 】 Objective To testify the effectiveness of maximal androgen blockade in the treatment of prostatic carcinoma. Methods from May 1995 to Jan.1997,23 cases of stage C or D prostatic carcinoma were treated with maximal androgen blockade (castration+flutamide) and another 23 with a retarder of androgen receptor (flutamide alone). Results Maximal androgn blockade was found to be more effective in the decrease of PSA level and the prostatic volume.A complete or partial response to maximal androgen blockade was observed in 65%,being significantly higher than that in flutamide alone (39%). Conclusions maximal androgen blockade was believed to be more effective and feasible in the treatment of prostatic carcinoma.

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