摘要 用放射免疫方法测定117例前列腺疾病患者血清游离PSA(F-PSA)、总PSA(T-PSA)值,并计算游离与总PSA比值(F/T比值)。其中前列腺癌31例,前列腺增生86例。结果显示:F/T比值前列腺癌组明显低于前列腺增生组(P<0.01)。认为F/T比值可用于区别前列腺癌与前列腺增生，尤其当PSA水平限定在4～10μg/L范围内,应用F/T比值较PSA为优。

The percentage of free to totalprostate specific antigen——A method in detectingprostate carcinoma Fang Zujun, YangLiuping,Song Jianda,et al.Department of Urology,Hua Shan Hospital,Shanghai MedicalUniversity,Shanghai 200040

     Abstract Serum free prostate specific antigen (F-PSA) and total PSA weremeasured with immunoradiometric assay and free/total PSA ratio was studied in 117patients. Among them,31 were prostatic carcinomas and 86 BPH.It was found that free/totalPSA ratio is lower in patients with CaP than in those with BPH.It was believed thatfree/total PSA ratio can be used in the differential diagnosis of CaP, especially whenserum PSA level is within between 4～10μg/L.

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