武桂珍 贾志远 黄玉英 龚晓红 李燕婷 李守邦 杨超美 刘建地 李敏 李志仁 曹惠霖 武桂珍、黄玉英 100050 北京，中国预防医学科学院疾病控制处；贾志远、曹惠霖 中国预防医学科学院病毒学研究所；龚晓红 北京市卫生防疫站；李燕婷 海市卫生防疫站；李守邦 吉林省卫生防疫站；杨超美 四川省卫生防疫站；刘建地 甘肃省卫生防疫站；李敏 湖北省卫生防疫站；李志仁 黑龙江省卫生防疫站 中华流行病学杂志 1999 0 20 5


    关键词：乙型肝炎疫苗；接种率；乙型肝炎表面抗原 期刊 zhlxbxzz 0 论著 fur -->


    

【摘要 】 目的 了解乙型肝炎疫苗的免疫后效果。方法 于1997年9～12月在北京、武汉、哈尔滨、上海、成都、兰州和长春7个城市，采用整群随机抽样方法抽取3～4岁年龄组儿童2180人进行调查。结果 1993～1994年新生儿乙型肝炎疫苗全程接种率城区为91.10%，明显高于郊区的84.71%。HBsAg阳性率降至1.56%，抗-HBs阳性率平均为70.50%。城区儿童HBsAg阳性率0.28%，郊区儿童HBsAg阳性率为2.17%，说明免疫儿童中HBsAg阳性者的主要来源在郊区。结论 上述表明，我国乙型肝炎疫苗免疫效果显著，但在郊区，疫苗免疫效果还不够理想。

    

A study on hepatitis Bvaccination of newborns in seven provincial capital cities and suburbs

WU Guizhen,JIA Zhiyuan,HUANGYuying,et al.

Institute of Virology, ChineseAcademy of Preventive,Beijing 100050

【 Abstract 】 Objective In order to investigate the effectiveness of hepatitis Bvaccination programmes in different regions in China. Methods A randomized sampling survey was carried out. A totalnumber of 2 180 children, aged 3-4 years old, were selected in 7 cities (Beijing,Wuhan,Harbin,Shanghai,Chengdu,Lanzhou and Changchun) during Sep-to Dec.1997.Results The rate ofHB immunization in the cities (91.10%) was significantly higher than that in relatedsuburbs (84.71%). The carrier rate of HBsAg decreased from 10% to 1.56% and anti-HBspositive rate was 70.50%. The carrier rate of HBsAg was 0.28% in the cities, compared with2.17% among the children in suburbs. Most unvaccinated children were in suburbs,making upthe main source of HBsAg positive children. Conclusion The effectiveness of the hepatitis B vaccination wassatisfactory, but the programme should be strengthened in suburbs.

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