蔡柏蔷 高志 罗慰慈 100730 中国医学科学院、中国协和医科大学 北京协和医院呼吸内科(蔡柏蔷、罗慰慈)；山东省滕州市中心人民医院(高志) 中华内科杂志 1998 0 0 11


    关键词：结节病，肺；肽基二肽酶A 期刊 zhnkzz 0 论 著 fur -->


    

【摘要 】 目的 提高对首发于肺外表现的结节病的认识。方法 回顾性分析了22例肺外结节病的临床资料，所有病例均有病理检查资料。结果 6例患者的首发肺外表现为周围淋巴结肿大，5例为皮肤改变，2例为眼部症状，3例为腮腺结节病，3例为骨关节炎，1例为心脏结节病，1例为肝脾肿大，1例为神经精神症状。部分肺外结节病的胸部X线检查正常，血管紧张素转化酶亦在正常范围内。结论 某些以肺外表现为首发症状的结节病可能尚处于疾病的早期阶段，故早期诊断和治疗有助于缓解肺外症状，提高治愈率。

Extrapulmonary sarcoidosis of a clinical analysis Cai Baiqiang, Gao Zhi, Luo Weici. Department of Respiratory Diseases, Peking Union Medical College Hospital,Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730

【Abstract 】 Objective Toimprove the recognition of sarcoidosis with extrapulmonary manifestations as presentingsymptoms. Methods The clinicalmanifestations and laboratory data of 22 cases of extrapulmonary sarcoidosis wereanalyzed. Results The clinical datawere as follows: 6 patients presented with lymphadenopathy as the initial involvement, 5cutaneous lesions, 2 ophthalmic involvement, 3 parotid sarcoidosis, 3 arthriticmanifestations, 1 cardiac sarcoidosis, 1 hepatomegaly and splenomegaly and 1 neurologiccomplication. Chest X-ray was normal and the levels of serum angiotension convertingenzyme were not elevated in some of the patients. Most of patients were treated withsystemic steroids and had the successful control of extrapulmonary manifestations. Conclusion Some cases of sarcoidosis which manifested with extrapulmonaryinvolvement as initial signs or symptoms may be in the early stage of the disease. Toestablish the diagnosis of sarcoidosis early and treat the patients with suitable regimenare essential to improve the outcome of extrapulmonary sarcoidosis.

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