辛绍杰 王松山 程云 王林杰 李静 薛生 罗清华 郭仁峰 李伯安 曹阳 张建宗 100039 北京，解放军302医院 中华肝脏病杂志 1998 0 0 1


    关键词：庚型肝炎病毒 原位杂交 免疫组化 期刊 zhgzbzz 0 庚型肝炎 fur -->


    

【摘要】 目的 研究HGV RNA及HGV抗原在肝组织中的表达。 方法 对17例HGV血清标志阳性患者进行了肝组织HGV RNA的原位杂交及免疫组织化学研究。 结果 原位杂交HGV RNA阳性8例，阳性率47.05%，阳性信号均存在于肝细胞的胞浆中；免疫组化3例HGV NS₅ 抗原阳性，阳性率17.64%，均为胞浆型。 结论 HGV RNA及HGV NS₅ 抗原阳性细胞及其周围肝细胞未见特殊病理改变。

    

EXPRESSION OF HGV RNA ANDHGV NS5 ANTIGEN IN LIVER TISSUES OF PATIENTS WITH VIRAL HEPATITIS

Xin Shaojie, Wang Songshan,Cheng Yun, et al. 302 Hospital of PLA, Beijing 100039

【Abstract】 Objective To studythe expression of hepatitis G virus (HGV) RNA and HGV NS5 antigen in the liver tissues. Methods Theexpression of HGV RNA and HGV NS5 antigen in the liver tissues were detected with in situhybridization and immunohistochemistry. Results The positive rate of HGV RNA and HGV NS₅ antigenexpressed in the liver tissues were 47.05% and 17.64%, respectively. Conclusion Thepositive substances of HGV RNA and HGV NS₅ antigen were both in cytoplasm ofthe hepatocytes. The positive hepatocytes and the hepatocytes surrounding these positivecells have no specific pathologic changes.

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