关键词:周围神经;静脉移植;雪旺细胞
【摘 要】 目的: 探寻静脉翻转后对引导神经再生的影响,为周围神经缺损的修复提供一种新方法。方法 :静脉段取出后,先将其内外翻转成一外膜在内,内膜在外的翻转静脉。然后再用此翻转静脉段桥接修复大鼠自体坐骨神经10mm缺损(IOVG)并与常规静脉桥接修复方法(CVG)进行对比研究。术后5个月,进行神经电生理及组织形态学检测。结果 :与CVG相比,IOVG组再生神经纤维的数目、髓鞘厚度、纤维直径以及运动神经传导速度均有提高。结论 :翻转静脉桥接修复周围神经缺损是一简单而有效的新方法。
AN EXPERIMENTAL STUDY OF TUBULATING A DEFECTOF PERIPHERAL NERVE WITH INSIDE-OUT VEIN GRAFT IN RAT
Chen Shulian, He Changqing, Wu Xuejian.
Department of Orthopedics, Henan Provincial Peoples Hospital, Zhengzhou 450003
【ABSTRACT】 Objective: In order toprovide a new method to repair peripheral nerve defect, this article detects the influenceon nerve regenerating. when using inside-out vein graft to bridge the gaps in peripheralnerve. Methods : Turn the harvested vein segment to bridge 10mm defect ofsciatic nerve in rat IOVG, and compared it with convential vein grafe (CVG).By 5 monthspostoperatively, the quantitative analysis in histology and the nerve electrophysiologicaltest were performed. Results : The number, the mylin sheath thickness andthe conduction velocity of the regenerating fibers had been improved in IOVG. Conclusion: Bridging a defect in peripheral nerve with inside-out vein graft is a simple and moreeffective method.
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