杨斌 赵敏 刘珍君 熊斌 刘元波 陈建 靳小雷 北京，中国医学科学院中国协和医科大学整形外科医院 100041 中华整形烧伤外科杂志 1999 0 15 3


    关键词：贴敷骨移植；再血管化 期刊 zhzxsswkzz 0 论 著 fur -->


    

【摘要】 目的 采用Wistar大鼠对颅骨(膜内成骨)和髂骨(软骨成骨)贴敷移植后早期再血管化进行了观察研究。方法 用计算机图像处理进行定量分析。结果 骨移植7天后，软骨成骨与膜内成骨血管密度分别为：22.33%和11.88%；14天时分别为34.93%和15.93%。结论 软骨成骨移植后较膜内成骨有更加迅速的血管化。文中对骨移植后骨质结构，血管化以及骨质体积存留之间的关系进行了讨论。

Comparative study on earlyrevascularization of membranous and endochondral onlay bone grafts in the rat

YANG Bin,ZHAO Min,LIU Zhenjun, etal. Plastic Surgery Hospital of Chinese Academy of Medical Sciences,Beijing 100041

【 Abstract 】 Objective Toinvestigate the disparity in early revascularization of the membranous and endochondralbone grafts.Methods Twenty Wistar rats were randomly divided into twogroups of 10 each.Full-thickness cranial(membranous)and split-thickness iliaccrest(endochondral)onlay bone grafts were placed subperiosteally onto the snout of theanimal without bony fixation.At 7 and 14 days after grafting the bone grafts together withthe recipient sites were harvested.Revascularization was studied utilizing opacifyinginjection and computerized image analysis technique.Results The extent ofvascularization at 7 days was 11.88% and 22.33% in membranous and endochondral bonegrafts,respectively,and they developed to be 15.93% and 34.93% at 14 days,respectively.Conclusion The results indicated that endochondral bone grafts were more rapidly revascularized thanmembranous bone grafts at 7 and 14 days (P<0.05).Differences in graft architecture aretheorized to account for the relationship between the vascularization and volumemaintenance in the bones of different embryonic origin.

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