陈辉 王宪刚 吉士俊 赵国贵 王常林 110003 沈阳， 中国医科大学第二临床学院小儿外科 中华小儿外科杂志 1998 0 0 5


    关键词：脊髓；脊髓拴系综合征；病理；终丝；脂肪瘤 期刊 zhxrwkzz 0 论 著 fur -->


    

摘要 目的：为观察脊髓拴系综合征患儿终丝及脂肪团块的病理改变，探讨其发病机制。方法： 对18例患儿术中取材， 行光镜、电镜观察。结果： 发现在终丝末端及脂肪瘤内，光镜下可见有大量的各种形态神经组织分布；电镜下见终丝内神经纤维髓鞘厚薄不均、 电子密度高低不等，轴浆内线粒体呈缺氧性改变； 随年龄增长， 病理改变加重。结论：观察证实了神经被拴系、 神经缺血、缺氧改变为本病的病理基础及本病早期治疗的必要性。

    Pathological Changes of Tethered Cord Syndrome Chen Hui, Wang Xiangang, Ji Shijun et al. Dept. of PediatricSurgery. The 2nd Clinical Hospital of China Medical University, Shenyang 110003

    Abstract Objective: To record the pathological changes of filum terminaleand lipoma in patients suffering from tethered cord syndrome(TCS). Methods: Filumterminale and lipoma removed during surgery were studied with microscopy andelectro-microscopy. Results: Light microscopy revealed nerve tissue of various formswhereas electromicroscopy showed that myelin sheath was of heterogenous thickness anddensity. Mitochondria in axon revealed anoxic changes. These changes became more prominentin older children. Conclusions: The study suggests that ischaemia and anoxia oflumbosacral cord are involved in tethered cord syndrome. It emphasizes the necessity ofearly treatment.

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