李宝兰 李琦 许绍发 张国红 东博涛 101149 北京市结核病胸部肿瘤研究所 中华结核和呼吸感染 1998 12 21 12


    关键词：肺肿瘤；肺活量；肺切除术 期刊 zhjhhhxgr 0 论 著 fur -->


    

【摘要 】 目的 研究肺癌患者围术期换气功能的改变规律及影响机制。方法 用氧合指数(P/F)、动脉肺泡氧分压比(a/A)、动脉血氧饱和度50%的氧分压(P₅₀ O₂ )、动脉血二氧化碳分压(PaCO₂ )4项指标对68例50岁以上男性肺癌患者分别于术前、术后即日、1、2、3、7日围术期换气功能进行监测。结果 肺癌术后3日内P/F、a/A较术前显著降低(P<0.01);PaCO₂ 、P₅₀ O₂ 术后即日较术前显著增加(P<0.01);术后2日内全肺切除氧合功能降低大于肺叶切除(P<0.05);低肺功能患者术后换气及通气功能障碍较肺功能正常者显著(P<0.05)。结论 肺癌术后3日换气功能明显减退,尤以氧合功能降低显著。应重点监测氧合功能变化,加强全肺及低肺功能患者的换气功能监测。

Study on gasexchange of the patients with lung cancer in perioperation

Li Baolan, Li Qi, XuShaofa,et al. Cardiopulmonary Laboratory, Beijing Tuberculosis & Thoracic ResearchInstitute, Beijing 101149

【 Abstract 】 Objective To study changes of gas exchangein perioperative patients with lung cancer. Method Indices including P/F,a/A, P₅₀ O₂ andPaCO₂ on gas exchange in 68 male patients(50-78y) with lung caner weremonitored on preoperative day 1 2 3 and postopertive day 7. Result Comparing with preoperation dataP/F a/A decreased significantly in 3 days(P<0.01) and PaCO₂ P₅₀ O₂ incresesd significantly on the day after operation (P<0.01), especially in the group ofpneumonectomy and abnormal ventilation,hypoxemia measured in preoperation. Conclusion The gas exchange of the patientswith lung caner reduced significantly in postoperative 3 days.

     【 Keywords 】 Lungneoplasms Vitalcapacity Pneumonectomy

迄今为止,手术治疗仍是肺癌患者的首选治疗方案 ......

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