尹玲 马明信 赵瑞琳 尹玲 赵瑞琳 1000034 北京，北京医科大学第一医院妇产科；马明信 血液科 中华围产医学杂志 1998 0 1 3


    关键词：妊娠；骨髓增生异常综合征 期刊 zhwcyxzz 0 论 著 fur -->


    

【摘要】 目的 探讨妊娠合并骨髓异常增生综合征的发生率、孕产期诊断、治疗和预后。 方法 回顾性分析1992年1月至1997年12月期间住院分娩的妊娠合并骨髓异常增生综合征6例，并复习文献。 结果 妊娠合并骨髓异常增生综合征发生率为0.66‰，占女性MDS人群的24%。6例中2例因病情严重而终止妊娠；产后出血超过500毫升者3例；合并妊娠高血压综合征2例；因产科指征剖宫产2例。全部患者在孕产期均需输血治疗、终止妊娠前应用激素及产后用抗生素预防感染。 结论 预防出血和感染是处理的关键。

    The Management for Pregnancy Complicated with Myelodysplastic Syndrome YinLing, Ma Mingxin, Zhao Ruilin. Department of Obstetrics and Gynecology, First Hospital,Beijing Medical University, Beijing 100034

    【Abstract】 Objective To investigate the incidence of pregnancycomplicated with myelodysplastic syndrome(MDS) and the influence between pregnancy and MDSand to discuss the diagnosis, treatment and prognosis of pregnancy complicated with MDS. Methods Sixpregnant patients complicated with MDS from Jan, 1992 to Dec, 1997 were retrospectivelyanalysed and literature was reviewed. Results The incidence ofpregnancy complicated with MDS was 0.66‰ and 24% of women with MDS were pregnantwomen.Therapeutic induction of labor was done in 2 cases because of severe MDS. Twocomplicated with PIH, and three complicated with postpartum haemorrage in six cases. Bloodtransfusion was necessary in all cases for treatment of severe anemia in pregnancy. MDSmay remit after delivery. The use of corticosteroid before termination of pregnancy andprophylactic antibiotics after delivery is important. Conclusions Itis important to prevent haemorrage and infection in the management of pregnancycomplicated with MDS .

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