李立伟 金泉 刘京璇 100036 北京，解放军空军总医院核医学科PET诊断中心 中华放射学杂志 1999 0 33 4


    关键词：体层摄影术；发射型计算机；肿瘤；诊断，放射性同位素 期刊 zhfsxzz 0 影像技术学 fur -->


    

【摘要】 目的 对¹⁸ 氟脱氧葡萄糖正电子发射体层显像在临床各种肿瘤性疾病诊断中的初步应用体会作一介绍。方法 正电子发射体层显像检查共计16例，所有患者静脉注射¹⁸ 氟脱氧葡萄糖(370～555 MBq)后40分钟进行代谢显像，其结果与同期的CT、MRI和(或)手术病理结果进行比较。结果 15例肿瘤病人中， 正电子发射体层显示所有病灶的¹⁸ 氟脱氧葡萄糖摄取均明显增高，与CT、MRI诊断相符者占73%，进一步肯定CT、MRI的结论者占27%，其中12例经手术病理证实；另1例脑梗死病例临床、CT和MRI诊断为乳腺癌术后脑转移，而正电子发射体层显像诊断为脑梗死，经临床对症治疗后好转。结论 初步的临床应用结果显示，正电子发射体层显像在全身各种肿瘤性疾病的诊断中具有明显的优势。

Preliminary clinical application of ¹⁸ F-FDG PET in oncology: compared with CT,MRI and/or pathology in 16 cases

LI Liwei, JIN Quan, LIU Jingxuan. PET Diagnostic Center of Nuclear Medicine Department, General Hospital of Air Force, Beijing 100036

【Abstract】 Objective To review the preliminary clinical application of ¹⁸ F-FDG PET in the field of oncology. Methods ¹⁸ F-FDG PET was performed in total 16 cases. All patients received intravenous administration of ¹⁸ F-FDG 370～555MBq, followed by a 40 minutes uptake phase, and subsequent PET scanning. The results of ¹⁸ F-FDG PET were compared with CT, MRI and/or pathology. Results In 15 cases of neoplasm, FDG uptake increased significantly for all lesions. And ¹⁸ F-FDG PET findings were consistent with or further confirmed the CT or MRI diagnosis in 11(73%) and 4(27%) cases. In one case mistaken for intracranial metastasis based on CT andMRI, correct diagnosis of infarction was made after glucose metabolism study with PET and confirmed after clinical treatment and follow-up. Conclusions Preliminary clinical application of ¹⁸ F-FDG PET has demonstrated its significant advantages in evaluating malignant diseases.

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