徐惠珍 李 园 沈 彬 朱精强 龚日祥 徐惠珍 朱精强 龚日祥 华西医科大学附属第一医院普外科(成都 610041)；李 园 沈 彬 华西医科大学附属第一医院外科研究生 中国普外基础与临床杂志 1999 0 6 5


    关键词：Crave′s病；促甲状腺激素受体抗体；诊断；治疗 期刊 zgpwjcylczz 0 临床研究 fur -->


    

摘要 探讨Crave′s病患者血清中促甲状腺激素受体抗体(thyrotropinreceptor antibody, TRAb)与其病情的内在联系，自1996年8月至1998年6月对156例门诊Crave′s病患者的血清TRAb进行检测并进行临床观察。结果：初诊Crave′s病患者90.1%血清TRAb升高；经抗甲状腺药物治疗后的患者，当血清甲状腺激素水平正常时，血清TRAb恢复正常；经药物或手术及¹³¹ I治疗后的复发病例，血清TRAb值升高。故血清TRAb水平与Crave′s病病情有密切的相关性。结论：血清TRAb水平的测定对于Crave′s病患者的诊断、治疗及随访均有重要意义。

CLINICAL SIGNIFICANCE OF SERUM THYROTROPINRECEPTOR ANTIBODY IN GRAVE′S DISEASE (REPORT OF 156 CASES)

Xu Huizhen, Li Yuan, Shen Bin et al.

    Department of General Surgery, First Affiliated Hospital of West China University ofMedical Sciences, Chengdu 610041

Abstract To study the relationshipbetween the level of serum thyrotropin receptor antibody (TRAb) and the severity of Crave′sdisease. From August, 1996 to June, 1998, 156 outpatients with Crave′s disease werefollowed up. The level of serum TRAb were measured by radio-receptor-analysis (RRA).Results: ①The level of serum TRAb rose in 90.1% of the untreated group; ②The level ofserum TRAb restored to normal after the antithyroid drugs were used and the thyroxinelevel in serum returned to normal; ③In recurrent patients with the treatment of ¹³¹ I,drugs or operation, the serum TRAb level increased. Conclusion: The level of serum TRAbhas great significance in the diagnosis, treatment and follow up of the Crave′s disease.

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