关键词:肝纤维化;肝静脉多普勒;血清标志物
摘 要 目的:比较肝静脉多普勒超声和血清标志物检测诊断肝纤维化的价值。方法:用上述二种方法同时对70例慢性肝病患者和40例正常人进行检测。结果:慢性肝病患者肝静脉多普勒波形改变具有相对恒定的特征变化;血清透明质酸(HA),Ⅲ型前胶原(PCⅢ)和层粘蛋白(LN)水平比正常对照组显著增高。结论:肝静脉多普勒法诊断肝纤维化明显优于血清法,是诊断肝纤维化较可靠的无创伤性方法。
Diagnosis of Liver Fibrosis byDoppler Ultrasound Assessment of Hepatic Veins Compared with Serological Investigation ofFibrosis Parameter
Yin Jun,Yin Ling,Zhou Xingxiang,et al
Department of Function,Fuling Central Hospital,Chongqing 408000
ABSTRACT Objective:To compare theclinical value of Doppler ultrasound examination of the hepatic veins and serologicalindicators test in diagnosis of hepatic fibrosis.Methods:Seventy chronic liver diseasedpatients were tested by Doppler ultrasound of the hepatic veins and serologicalindicators(hyaluronic acid,procollagen type Ⅲ,Laminin),40 normal served as thecontrol.Results:The features of chronic liver disease changes in Doppler waveform of thehepatic veins remained stable.The serum hyaluronic acid(HA),procollagen type Ⅲ (PCⅢ),Lamininlevel in patients with chronic liver disease were significantly higher than that incontrol group.Conclusion:The Doppler ultrasonography of hepatic veins was better thanserological tests for the diagnosis of hepatic fibrosis.
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