【摘要】

    目的 探讨促性腺激素释放激素激动剂(GnRHa)对子宫肌瘤患者血红蛋白及红细胞压积的影响。

    方法 30例子宫肌瘤患者应用GnRHa 2～4个月，于停药4～6周手术，比较用药前及术前血红蛋白、红细胞压积、血清性激素水平、子宫及肌瘤缩小程度。

    结果 应用GnRHa后，血红蛋白及红细胞压积均明显上升，血红蛋白由(94.27±20.46)g/L上升至(114.40±19.91)g/L，红细胞压积由(29.41±4.96)%上升至(34.14±5.28)%，贫血率由70%下降为33.33%，治疗前后比较，差异有非常显著性(P<0.01)。治疗后血清性激素水平明显下降(P<0.01)。子宫及肌瘤体积均明显缩小(P<0.01)，子宫体积缩小(42.77±12.11)%，肌瘤体积缩小(37.65±15.20)%。

    结论 GnRHa通过使子宫肌瘤患者月经量减少或闭经，从而提高子宫肌瘤患者血红蛋白及红细胞压积水平。

    关键词 促性腺激素释放激素激动剂 子宫肌瘤 血红蛋白 红细胞压积

    Observation on effects of gonadotrophin releasing hormone agonist on hemoglobin and haematocrit of uterine leiomyoma patients

    Lv Hua,Xia Enlan,Cheng Jiumei,et al.

    Department of Obstetrics and Gynecology,Beijing Haidian Hospital,Beijing 100080.

    【Abstract】

    Objective To investigate effects of gonadotrophin releasing hormone agonist (GnRHa) on hemoglobin and haematocrit of uterine leiomyoma patients.

    Methods 30 patients with uterine leiomyoma were treated by GnRHa for 2 to 4 months,and then operations were performed at 4 to 6 weeks after the last injection.Hemoglobin,haematocrit,sex hormonal parameters,uterine and uterine leiomyoma volume were compared before and after treatment. ......