【摘要】 目的 探讨急性等容血液稀释用于脊柱手术对减少输注异体血的效果。 方法 择期行脊柱手术患者20例，随机分成血液稀释组(A组)和对照组(B组)，麻醉选择静吸复合全麻。A组于麻醉后手术前行急性等容血液稀释(ANH)，B组不作血液稀释。术中根据出血量分别输注自体血(A组)或异体血(B组)。记录病人的采血量(A组)、术中出血量、输异体血量(B组)、补液量和尿量，以及围术期Hb和HCT变化。 结果 A组术前采血量为(1055±237)ml，两组术中出血量比较无统计学差异，B组术中输注异体血量为(660±190)ml，A组回输自体血，无需异体血，A组术中补液量多于B组(P<0.01)，术中两组尿量无统计学差异。两组术后Hb和HCT均显著低于术前水平(P<0.01)，但仍维持在安全范围，两组病人术中呼吸循环功能均维持平稳，术后均未发现肾功能异常。 结论 急性等容血液稀释用于脊柱手术可避免输注异体血。

    【关键词】 血液稀释;麻醉;全身;脊柱手术

    【Abstract】 Objective To explore the effect of acute normovolemic hemodilution(ANH)on reducing the need of allogeneic blood.Methods Twenty ASAⅠ～Ⅱpatients aged25～65yr，scheduled for spinal column orthopaedics were randomized into two groups:hemodilution group(group A)and control group(group B).All patients were re-ceived general anesthesia.In the hemodilution group(group A)，acute normovolemic hemodilution were performed just after induction of anesthesia.Blood was withdrawn from radial artery while equi-volume of6%hydroxyethyl starch(6%HES200/0.5)were transfused through vein with hemodilution to a HCT of30%.During the operation ......