鼻咽癌放疗前后应用彩色多普勒超声监测颈部转移淋巴结的价值
放射治疗,,鼻咽癌；放射治疗；转移淋巴结；彩色多普勒,1资料与方法,2结果,3讨论,【参考文献】
【摘要】 目的 在鼻咽癌放疗前后应用彩色多普勒超声跟踪监测颈部转移淋巴结二维灰阶声像和血供变化，提供放疗补量依据。方法 对48例鼻咽癌伴颈部淋巴结转移患者采用放射治疗，在放疗前、放疗后(65Gy时)应用彩色多普勒超声检测颈部转移淋巴结的消退程度和血供情况。结果 48例鼻咽癌颈部淋巴结转移患者放疗前转移淋巴结血流强度以2～3级为主；放疗后血流强度以0～1级为主，差异有显著性(P<0.05)。放疗前，收缩期峰值流速(SPV)(20.63±9.36)cm/s，阻力指数(RI)0.59±0.08；放疗后 SPV (13.88±9.60)cm/s，RI 0.73±0.14，差异有显著性(P<0.05)。淋巴结的消退程度与血供呈正相关。结论 鼻咽癌放疗前、后应用彩色多普勒超声监测颈部转移淋巴结的大小及血供变化,可初步判断放疗效果并可作为增加放疗剂量依据之一。【关键词】 鼻咽癌；放射治疗；转移淋巴结；彩色多普勒
The dynamic value of color Doppler flowing imaging in metastatic cervical lymph nodes of nasopharyngeal carcinoma before and after irradiation
ZHA Yue-qin,YU Zhi-ying,LIN He-ping,et al.
Department of Ultrasound,The First Affiliated Hospital of Suzhou University,Suzhou 215006,China
【Abstract】 Objective To measuring 2D gray scale imaging and the change of blood supply of nasopharyngeal carcinoma patients’metastatic cervical lymph nodes before and after radiotherapy by color Doppler flowing imaging (CDFI) and to offer boosting radiation dose evidence.Methods 48 nasopharyngeal carcinoma patients with metastatic cervical lymph nodes were enter into the study group. The blood supply and regressive degrees of these patients’ metastatic cervical lymph nodes were detected before and after irradiation(65Gy) by CDFI.Results Before irradiation,the blood flowing intensities of the 48 patients’ cervical lymph nodes were mainly in 2-3 grade,which were significant higher than those after irradiation,which they were mostly in 0-1 grade(P<0.05). The systole peak value flow-rate(SPV) and resistent index(RI) for the before irradiation group and after irradiation group were 20.63+9.36cm/s, 0.59+088 and 1388+960cm/s,073+014,respectively,which had significant difference(P<005). The lymph node regression degree was positively correlated with the blood supply. Conclusion To dectet the size and blood supply of metastatic cervical lymph nodes by CDFI could estimate the effect of radiotherapy of nasopharyngeal carcinoma patients and offer the evidence if it is necessary to boost the radiation dose. ......
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