摘要：目的：观察咪唑安定、氯胺酮和丙泊酚用于成年人特重烧伤削痂植皮术的麻醉效果。方法：选择18～71岁的特重烧伤病人41例，共行82次削痂植皮术，在保留自主呼吸下，单次静注咪唑安定0.1～0.15mg/kg，分次静注氯胺酮,首剂量1.5～2mg/kg，追加量为1mg/kg，持续泵注丙泊酚2～4mg/kg.h维持静脉麻醉，结果：82例次手术麻醉过程顺利，术后病人清醒快，恶心呕吐发生率低，满意率高。结论：咪唑安定、氯胺酮和丙泊酚用于成年人特重烧伤削痂植皮术的麻醉，用药量少，效果好，是较理想的麻醉方法。

    关键词： 咪唑安定； 氯胺酮； 丙泊酚； 特重烧伤； 削痂植皮术

    The clinical effect of Midazolam,Ketamine and Propofal on Tangential Excision and Skin Grafting for Severely Burned Patients

    JI Qin-quan， WU Li-juan， CHEN Xiang-qi

    (The Second Hospital of Shantou,Guangdong Shantou 515031,China)

    Abstract：Objective： To study the effect of anesthesia with midazolam,ketamine and propofol are used for tangential excision and skin grafting for severely burned patients.Method： 82 operations have been carried out on 41 adults,who were aged 18 to 71 and suffered severe burn.The patients being able to breathe normally,Anesthetize them with intravenous medazolam 0.1～0.15mg/kg all at time,Initial dose of ketamine is 1.5～2mg/kg ,repeated maintenance dose is 1mg/kg each time,propofol 2～4mg/kg.h continousy. Result: Anesthesia has been successful for 82 cases giving highly satisfaction,Patients recovered quickly with an low rate of sickness.Conclusion: Using midazolam,ketamine and propofol for clinical study of anesthesia for tangential excision and skin grafting for severly burned patients.Only little dose is needed.The high efficiency proves that this a ideal way of anesthesia. ......