【摘要】 目的 观察尿激酶在急性心肌梗死治疗中的溶栓效果及安全性。 方法 对62例采用尿激酶150万U静脉溶栓治疗的急性心肌梗死的临床资料作回顾性分析。溶栓治疗时间为3～6h(46例<3h，16例<6h)。观察溶栓再通率、急性期死亡率以及副作用发生率;并比较溶栓组与未溶栓组死亡率。 结果 溶栓再通率为67.7%，5周死亡率8.0%，轻微出血倾向率16.1%。5周死亡率未溶栓组27.4%，溶栓组8.0%，两组比较死亡率有统计学显著差异(P<0.01)。 结论 尿激酶为治疗急性心肌梗死有效和安全的溶栓药物。

    【关键词】 心肌梗死;尿激酶;溶栓治疗

    Clinical observation using intravenous urokinase for thrombolytic therapy in pa-tients with acute myocardial infarction

    LV Jing-dong，HUANG Shi-an，ZHANG Bao-min，et al.

    Department of Internal Medicine，the People's Hospital of Dangshan，Anhui235300，China

    【Abstract】 Objective To observe the clinical efficacy and safety of intravenous thrombolytic therapy using uroki-nase(UK)in acute myocardial infarction(AMI).Methods 62patients with AMI who were treated by intravenous UK1.5million units were retrospectively analyzed.The time from onset of symptoms to thrombolytic therapy was3～6hours ......