摘要：目的：观察Graves病在临床内科治疗中，彩色多普勒超声检测的临床意义。方法：选择60例经临床及实验室检查确诊且未予抗甲亢治疗的Graves病患者为治疗前组；其中经口服他巴唑治疗6个月后有效者44例为缓解组；无效者16例为未缓解组；另选择30例正常人为对照组。对比分析其各组甲状腺超声检查的有关参数值。结果：治疗前组甲状腺体积明显增大(主要由于甲状腺厚度明显增大所致)，左右基本对称，内部光点增粗，回声均匀或部分不均，血流信号丰富或极丰富，甲状腺上动脉的峰值血流速Vmax明显增高，与对照组及缓解组比较差异显著，P<0.05；未缓解组患者，经临床及时更改治疗方法(放射性碘治疗或手术治疗)，均获得了较好的疗效。结论：彩色多普勒超声在Graves病的临床治疗中有重要的指导意义。

    关键词：Graves病；治疗；彩色多普勒； 临床意义

    The Clinical Meaning of Color Doppler Ultrasound in Treatment of Graves Disease

    WEN Ci-xiang，LIAO Gui-ying，XIE Ying-cai，et al

    (The Affiliated Hospital of Guangdong Medical College，Guangdong Zhanjiang 524001, China)

    Abstract： Objective: To explore the clinical meaning of color Doppler’s ultrasound in treatment of Graves. Method: To select 60 patients contracting Graves as the pretreatment group which is confirmed by clinical and laboratory examination that they have not received antihyperthyroidism treatment before. After six-month treatment of Thiamazole, 44 responders are considered as the remission group, while 16 no responders as the non-remission group. Besides, 30 healthy subjects are selected as control group. Then compare and analyze the related parameter of the thyroid ultrasound in each group. Result: In the pretreament group , thyroid glands are swollen, which are mainly because they are thicker than other groups. Thyroid glands are symmetry, light spot tickening in the internal of thyroid, reflecting ultrasonic evely or unevely, with an abundant blood flow. The maximum blood flow velocity(Vmax) of the patients’ arteries are increased than in remission and control group(P<0.05). After treated with modified therapeutic strategy(radioiodine therapy or operation), the non-remission patients get a better curative effect. Conclusion: Color Doppler ultrasound have important instructional significance in treatment of Graves. ......