摘要：目的：观察米多君治疗血液透析相关性低血压的疗效。方法：16例血液透析相关性低血压患者，血液透析前或既往低血压出现前30min口服米多君5～10mg/次，透析处方不变，观察透析中低血压发生情况。结果:16例192例次米多君治疗患者血液透析中脱水速度，透析液电解质浓度，透析温度及透析前血压均无显著性差异(p>0.05)； 观察期内红细胞压积，血浆白蛋白均无显著性差异(p>0.05)；米多君治疗后总脱水量，Kt/v，透析中最低血压及透析后血压均高于治疗前(p<0.05)，低血压发生例次，症状性低血压发生例次均低于治疗前(p<0.05)，其中显效9例(56.2%)，有效4例(25%)，无效3例(18.8%)。结论:米多君治疗血液透析相关性低血压有效且安全。

    关键词：慢性肾功能衰竭；盐酸米多君；血液透析；低血压

    Midodrine Treatment for Patients with Hemodialysis Associated Hypotension

    LUAN Shao-dong，MA Bin，HE Yong-cheng，et al

    (Shenzhen Second People’s Hospital, Guangdong Shenzhen 518035, China)

    Abstract：Objective: To evaluate efficacy of midodrine in treatment of hemodialysis associated hypotesion. Method: Midodrine(5～10mg) was employed in 16 hemodialysis associated hypotesion patients at the start of dialysis or 30 minutes before occurrences of past recorded intradialysis hypotension with same hemodialysis prescription. Result: The ultrafiltration rate, dialysate electrolyte concentration, dialysate temperature and blood pressure levels prior to dialysis were similar during pre and post midodrine administration periods(p>0.05). Hematocrit and serum albumin had no statistically differences during observation period. Ultrafiltration volume, Kt/v ......