聚合物纳米颗粒的制备及其应用(I)
通过聚合反应制备纳米颗粒
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文章编号：(2003)03-0124-13,通过聚合反应制备纳米颗粒
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徐 晖，郑俊民，潘 研， 周 蕾，魏兰兰
(沈阳药科大学药学院，辽宁 沈阳 110016)
摘要：目的 概述通过聚合反应制备纳米颗粒的研究进展。方法 对通过单体聚合反应制备纳米颗粒的方法、反应机理和应用进行介绍。结果和结论 聚合物纳米颗粒可以通过自组装表面活性剂的聚合反应，或者胶体体系中单体的聚合反应制备。这种纳米颗粒可用作药物传递的胶体载体。
关键词：药剂学；综述；纳米颗粒；自组织表面活性剂；胶团；囊泡；微乳
中图分类号：R94 文献标识码：A
Preparation and application of polymer nanoparticles ( I )
Nanoparticles obtained through a polymerization reaction
XU Hui, ZHENG Jun-min, PAN Yan, ZHOU Lei, WEI Lan-lan
(School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China)
Abstract: Objective To summarize the recent advances on polymeric nanoparticles. Methods The methods and mechanisms of obtaining nanoparticles through a polymerization reaction were discussed in detail. Results and Conclusions Polymeric nanoparticles can be prepared by polymerization of self-organized surfactant assemblies, or by polymerization of the monomer in colloids. Such nanoparticles may be used as colloidal carriers for drug delivery.
Key words: pharmaceutics; application; review; nanoparticle; self-organized surfactant; micelle; vesicle; microemulsion
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