【摘要】 目的 探讨霉菌性食管炎相关病因并讨论其防治方法。 方法 回顾分析从1993年10月～1999年10月我院内镜室118例霉菌性食管炎的临床表现、内镜下病理表现、治疗经过及其他相关因素。结果 所检病例占同期所有食管炎病人的1.07%。平均年龄44.5岁,男女之比 2.1:1，职业情况： 78例农民，占66.1%，17例工人，占14.4%，13例干部，占11.0%，其他10例，占8.5%。临床表现有吞咽困难、吞咽痛、胃灼热等。伴随消化性溃疡13例(17.8%)，胃癌3例(5.9%)，且多数为慢性胃炎。全部病例霉菌检查阳性。病理类型包括颗粒型(65例，55.1%), 斑片型(40例，33.9%), 糜烂溃疡型(13例，11%)。用大蒜素类制剂，制霉菌素和伊曲康唑等治疗，43例复查内镜，结果显示29例显效(67.4%),12例有效(21.9%),2例无效(4.7%)。结论 霉菌性食管炎近年来呈逐年上升趋势，其相关因素较多，特别应预防医源性因素所致的感染，应根据患者不同情况选用不同药物治疗。

    关键词 霉菌性食管炎 内窥镜

    Analysis on 118 cases with mycetogenic esophagitis

    Tang Chuankang,Deng Mingming,Mao Dengming, et al.

    Department of Gastroenterology,the First Affiliated Hospital of Luzhou Medical College , Luzhou 646000.

    【Abstract】 Objective To investigate the related causes of mycetogenicesophagitis and discuss the methods how to prevent and treat it.Methods We have analyzed the clinical manifestations,the pathological findings,the treatment and the other relative factors of 118 cases with mycetogenic esophagitis in endoscope room of our hospital from October 1993 to October 1999.Results These cases occupied 1.07 % of all esophagitis patients at the same period. We found that the average age of these cases is 44.5 years old , the ratio of male to female is 2.1 :1 , 78 cases:occupation farmer,account for 66.1% , 17 cases: worker, account for 14.4%, 13 cases: staff, account for 11% and the other 10 cases, account for 8.5%.The clinical symptomes of these patients include dysphagia,odynophagia,pyrosis etc. The accompanying diseases include 13 cases of peptic ulcer (17.8%), 3 cases of carcinoma of stomach(5.9%) and most patients have chronic gastritis. Mycetes inspection of all cases are positive. The types of pathomorphism inc-lude granular type (65cases, 55.1%),plaque type (40cases 33.9%), erosive and ulcerative type (13 cases,11%).We treated the patients with garlics,nystatines and itraconazoles etc. 43 cases had been repeated endoscopy , and the results showed that 29 cases had evident effect(67.4%), 12 cases had effect (21.9%), 2 cases had no effect (4.7%). Conclusion The mycetogenic esophagitis reports in recent years year by year up-trend, its relative factor is more, we should especially prevent the iatrogenic infection and according to the different condition to use the different medicine treatment. ......