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献血者血清抗-HCV阳性与ALT活性的关系
http://www.100md.com 《中国热带医学杂志》 2005年第4期
丙氨酸氨基转移酶,,抗-HCV;丙型肝炎病毒核酸;丙氨酸氨基转移酶,1材料与方法,2结果,3讨论,参考文献:
     摘要:目的 分析献血者血清抗-HCV抗体及丙型肝炎病毒核酸(HCV RNA)含量与ALT的关系。 方法 采用ELISA法检测抗-HCV抗体,阳性标本用荧光PCR试剂盒测定HCV RNA,分析ALT活性与HCV RNA水平的关系。 结果 83份抗-HCV抗体阳性标本经PCR检测后有37份标本含HCV RNA,HCV RNA拷贝量与ALT活性呈正相关,且标本的HCV RNA含量越多,ALT活性也越高(P<0.01)。 结论 献血者中筛查ALT并结合PCR技术,能减少HCV经血传播的危险。

    关键词:抗-HCV;丙型肝炎病毒核酸;丙氨酸氨基转移酶

    The relationship between anti-HCV positive and the activity of ALT in serum of blood donors.

    ZHONG Tu-quan,ZHANG Xiao-yun.

    (Zhanjiang Municipal Central Blood Station,Zhanjiang524002,Guangdong,P.R.China)

    Abstract:Objective To investigate the relationship betweem serum virus RNA and ALT levels in anti-HCV positive samples of donors. Methods Hepatitis C virus fluorescence PCR diagnostic kitwas carried out on the anti-HCV positive samples in order to reveal any possible relationship between HCV RNA and ALT levels. Results 37samples were tested positive for HCV RNA a-mong83anti-HCV positive samples.The more copies of HCV RNA in the blood samples ......

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