不同剂量比索洛尔治疗心力衰竭的效果
心力衰竭,,比索洛尔;β受体阻滞剂;剂量;心力衰竭
【摘要】 目的 探讨不同剂量比索洛尔(康可)对心力衰竭(简称心衰)的治疗效果,促进β受体阻滞剂在心衰治疗中的应用。方法 106例心衰患者随机分为康可2.5mg/d(A组)和康可5~7.5mg/d治疗组(B组),观察主要事件和指标的变化。结果 康可5~7.5mg/d治疗组较康可2.5mg/d组,心衰恶化及再住院显著减少,NYHA心功能和EF显著改善,对血压和心率控制更理想。结论 大剂量比索洛尔能更好地保护心脏,应积极使用β受体阻滞剂治疗心衰。【关键词】 比索洛尔;β受体阻滞剂;剂量;心力衰竭
Therapeutic effect on treating heart failure with different doses of bisoprolol
TANG Biao,LIU Ju-fang.
Department of Medicine,People’s Hospital of Yuechi County,Sichuan 638300,China
【Abstract】 Objective To test the effect on treating heart failure (HF) with β receptor blocker,improve the application of β receptor blocker on treating HF.Methods 106 patients with HF (NYHA degrees 2~4) were divided into Group A and Group B,Group A contains 51 patients with bisoprolol 2.5mg/d,and Group B contains 55 patients with bisoprolol 5~ 7.5mg/d orally respectively.Therapeautic effect were observed after 3~15 months in the followed.Results HF deterioration and rehospitalization in Group B is significantly lower (P<0.05).LVEF and NYHA degrees in Group B is significantly increased (both P<0.05).Conclusion The higher dose of bisoprolol is possibly more benefit to HF. ......
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