【摘要】 目的 研究梗阻性黄疸与肾功能损害因果关系，提出防治对策。 方法 对56例梗阻性黄疸并发肾功能损害的病例进行血清胆红素和血清肌酐水平及其相互关系分析，并进行术前、术后对照比较。 结果 血清胆红素水平与肾功能损害的发生率和损害程度呈正相关，严重感染及手术对机体内环境的影响，进一步加剧肾功能的损害。 结论 高胆红素血症、内毒素血症和有效循环血量的改变是肾功能损害的直接致病因素。实施早期综合防治，是保护肾功能、防止肾损害、降低病死率的根本而有效地措施。

    关键词 梗阻性黄疸 肾功能损害 防治

    The renal injury and its preventive treatment of the sufferers from the obstructive jaundice

    Ding Guoxiong，Yang Shanyu

    The Hospital of Hefei University of Technology，Hefei230009.

    【Abstract】 Objective To explore the causality between obstructive jaundice and the impairment to the renal function as well as the respective preventive treatment measures.Methods An analysis has been made of the level of serum bilirubin，creatinine and their correlation from the clinical observation of56cases of obstructive jaundice with renal impairment along with the comparison of the conditions before and after the operation.Results The level of-serum bilirubin shows the positive correlation with the incidence and the extent of impairment.Serious inflection and the influence from the operation on the body internal environment aggravate the impairment to the renal function.Con-clusion Hyperbilirubinemia ......