【摘要】 目的 探讨术中细针活检细胞组织学诊断在胰腺壶腹周围占位性病变的诊断价值。方法 对天津肿瘤医院，自1992年12月～2002年12月经手术治疗236例胰腺壶腹周围占位性病变行术中细针活检，所有病例均经病理证实其符合率。结果 236例中细针活检诊断找到恶性肿瘤细胞134例(56.8%)，未找到恶性肿瘤细胞为82例(34.7%)，6例(2.5%)为可疑，14例(5.9%)为取材不满意。无假阳性诊断，假阴性为9.4%。结论 胰腺壶腹周围占位性病变术中细针活检细胞学检查，对明确良恶性肿瘤诊断、指导术式选择是一种较实用，有效的方法。

    【关键词】 细针活检；胰腺及壶腹周围占位；细胞学诊断

    【Abstract】 Objective To evaluate the value for intraoperative fine needle biopsy (IFNB) in neoplasms of the pancreas and periampulla.Methods 236 cases of IFNB were retrospectively reviewed from Dec.1992 to Dec.2002.All the cases were followed up and compared with pathologic diagnosis.Results Out of 236 cases,for malignant cytologic findings 134 cases were positive,82 cases were negative,6 cases were suspicious,14 cases were undetactable due to unsatisfied sampling.There was no false-positive while the overall false-negative rate was 9.4%.Conclusion IFNB is a highly accurate cytologic technique of sampling neoplasma of the pancreas and periampullar,which is of great value in differentiating diagnosis and determing the way of operation. ......