血标本中检出52株产ESBLs革兰阴性杆菌的药敏分析
血标本,,血培养；产超广谱β内酰胺酶；败血症；药敏试验,1材料与方法,2结果,3讨论,参考文献：
摘要：目的 了解深圳市宝安区人民医院自血培养中分离出的产超广谱β内酰胺酶革兰阴性杆菌的药敏情况，为临床用药提供参考。 方法 对该院近三年来自血标本中分离的产ESBLs革兰阴性杆菌的药物敏感情况进行回顾性分析。 结果 共分离出52株产ESBLs大肠埃希菌和肺炎克雷伯菌，其中大肠埃希菌35株，肺炎克雷伯菌 17株。52株产ESBLs肺炎克雷伯菌和大肠埃希菌对亚胺培南的敏感率最高达962%。 结论 亚胺培南仍然是治疗产ESBLs革兰阴性杆菌引起败血症的首选用药。关键词：血培养；产超广谱β内酰胺酶；败血症；药敏试验
中图分类号：R44611 文献标识码：B 文章编号：1009-9727(2005)02-320-02
Analysis of the resistance of 52 strains of extendedspectrum β lactamases producing bacilli isolated from blood samples to antibioties XIANG Kai-fu, CUI Ying-peng, ZHONG Fu-xia, et al(Baoan District People’s Hospital of Shenzhen City, Shenzhen 518101, Guangdong, P R China)
Abstract:Objective To investigate the antibiotic resistance situation of the extendedspectrum β-lactamases producing bacilli isolated from blood specimen Methods Retrospective analysis of the antibiotic resistance situation of extendedspectrum β-lactamases producing bacilli isolated from the blood specimens of our hospital was perfomed in recent three years Results Totally 52 strains of the extendedspectrum β-lactamases producing Escherichia coli and Klebsiella pneumonia were isolated including 35 strains of Escherichia coli and 17 strains of Klebsiella pneumonia , the sensitive rate of 52 strains of extendedspectrum β-lactamases producing Escherichia coli and Klebsiella pneumonia to imipenem was most high up to 962% Conclusion Imipenem remains to be the first choice to cure the septicemia caused by broadspectrum β-lactamases producing bacilli ......
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