【摘要】 目的 本研究应用一种新的荧光分光光度法检测颞下颌关节紊乱病患者关节液中一氧化氮含量，探讨一氧化氮与颞下颌关节紊乱病的关系。方法 对77例颞下颌关节紊乱病患者，经临床及X线检查(包括双侧颞下颌关节开闭口位及患侧关节造影检查)分为三组：滑膜炎组、关节盘前移位组、骨关节病组。10名正常健康人作对照。采用改良荧光分光光度法检测下颌关节液中一氧化氮含量。结果 关节盘前移位与滑膜炎、骨关节病之间NO含量差异均有显著性(P<0.05，P<0.05)， 滑膜炎和骨关节病之间NO含量无明显差异。正常对照组有一例检测出微量一氧化氮(0.17μmol/L)，明显低于患者组。结论 一氧化氮与颞下颌关节紊乱病病理改变有关，炎性病变比单纯结构紊乱一氧化氮含量高。改良荧光分光光度法检测一氧化氮灵敏度高、操作简单、技术先进。

    【关键词】 一氧化氮；颞下颌关节紊乱病；滑液；荧光分光光度法

    Measurement of NO content in synovia of temporomandibular disorders patients

    CUI Jiang-tao，WANG Dong，CHANG Pan-hui.

    Second Hospital of Tianjin Medical University，Tianjin 300211，China

    【Abstract】 Objective To study the relationship between NO content and temporomandibular disorders (TMD) by improving fluorometric assay to measure NO content in synovia of TMD patients.Methods Chose 77 TMD patients randomly and divided them into three groups according to clinical examination and x-ray examination (panoramic transcranial views of closed mouth and arthrograpnic examination.): synovitis group ......