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幽门螺杆菌根除对门脉高压性胃病患者预后的影响
http://www.100md.com 凌安生, 朱 励, 王 龙,陈金联, 朱金水
Hpylori根除;门脉高压性胃病;疗效凌安生,朱励,王龙,陈金联,朱金水.幽门螺杆菌根除对门脉高压性胃病患者预后的影响.世界华人消化杂志2005;13(22)2708-27100引言,幽门螺杆菌根除
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     凌安生, 安徽省安庆市第一人民医院内二科 安徽省安庆市 246003

    朱 励, 王 龙, 陈金联, 朱金水, 上海交通大学附属第六人民医院消化科 上海市 200233

    通讯作者:朱金水, 200233, 上海市宜山路600号, 上海交通大学附属第六人民医院消化科. zhujs1803@hotmail.com

    电话:021-64369181-8969 传真:021-64837019

    收稿日期:2005-07-15 接受日期:2005-07-19

    Effect of Helicobacter pylori eradication onprognosis of patients with portal hypertension gastric disease: ananalysis of 106 cases

    An-Sheng Ling, Li Zhu, Long Wang, Jin-Lian Chen, Jin-Shui Zhu

    An-Sheng Ling, the Second Departmentof Internal Medicine, the First People’s Hospital of Anqing, Anqing246003, Anhui Province, China

    Li Zhu, Long Wang, Jin-Lian Chen, Jin-Shui Zhu, Department ofGastroenterology, the Sixth Affiliated People’s Hospital of ShanghaiJiaotong University, Shanghai 200233, China

    Correspondence to: Jin-Shui Zhu, Department of Gastroenterology,the Sixth Affiliated People’s Hospital of Shanghai Jiaotong University,600 Yishan Road, Shanghai 200233, China. zhujs1803@hotmail.com

    Received: 2005-07-15 Accepted: 2005-07-19

    Abstract

    AIM:To investigate the effect of H pylori eradication onpatients with portal hypertension gastric disease (PHGD).

    METHODS:One hundred and six patients with PHGD and Hpylori infection were randomly divided into control group (n =50, treated with omeprazole) and H pylori eradication group (n= 56, treated with omeprazole, clarithromycin, and amoxicillin).All the patients received gastric endoscopy and 14Cbreath test at the end of the experiment.

    RESULTS:Before the experiment, erosive gastritis was found in46 patients (45.8%). After treatment, the negative rate of H pyloriwas significantly different between the H pylori eradication andcontrol group (95.9% vs 6.1%, P?

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