摘 要: 本文介绍了青蒿素及其衍生物的基本研究状况和它们抗寄生虫病的研究进展，青蒿素及其衍生物主要的抗寄生虫作用表现为抗疟原虫和抗血吸虫，它们抗弓形虫、卡氏肺孢子虫、犬附红细胞体和球虫的作用也较强，对其进一步的研制和开发具有广阔的前景。

    关键词: 青蒿素;衍生物;抗寄生虫

    PROGRESS OF RESEARCH ON THE ARTEMISININ AND IT'S DERIVATION AGAINST PARASITISM

    ZHENG Jiao-mei， LUO Dong-sheng， LIU Yi

    (1.College of Science and Technology， Hunan Agriculture University， Changsha 410128， China; 2. Changsha Animal Epidemic Prevention and Supervise Station， Changsha 410006， China)

    Abstract: Qinghaosu(artemisinin)， also known as artesunate and artemether and dihydroartem isnine， is a new type of antimalarial drug isolated from Artemisa annua L， It can not only be used in the treatment of acute cer- ebral and malignant malaria and schistosoma， but also be used in the treatment of toxoplasmosis and coccdiosis， some ramification of artemisinin was reported have reliable suppressing and killing effects on Pneumocystis carinii and plasmobium berghei in mice.

    Key words: Artemisinin; treatment; anti-parasitism

     1 青蒿素及其衍生物

    青蒿素是我国首先研制成功的一种抗疟新药，其入药始载于168年左右，马王堆三号汉墓出土的 帛书<五十二药方>，宋、元、明、清各代药典和本草纲目等均有收录 ......