关键词: 康复;脑梗死;降钙素基因相关肽

    摘 要:目的 研究康复功能训练对脑梗死大鼠大脑降钙素基因相关肽(CGRP)表达的影响. 方法 采用60只SD大鼠制作脑梗死模型;24h后随机分为康复组和制动组;康复组每日给予平衡、抓握、旋转、行走等功能训练，制动组置于网状笼内固定，各组在24h，1，2，3和4wk检测CGRP表达. 结果 康复组和制动组大鼠中枢神经系统中皮质、脊髓前角均出现CGRP阳性神经元，康复组反应比制动组强. 结论 康复功能训练可引起CGRP表达增加，有促进神经功能恢复的作用.

    Effects of rehabilitative training on CGRP expres┐sion in brain of cerebral infracted rats

    LI Ling，YUAN Hua，XU Li

    Department of Physiotherapy and Rehabilitation，Xijing Hospital，Fourth Military Medical Universi-ty，Xi'an710033，China

    Keywords:rehabilitation training;cerebral infarct;calcitonin gene-related peptide

    Abstract:AIM To study the effect of rehabilitation training on the expression of calcitonin gene-related peptide(CGRP)in the brain of cerebral infracted rats.METHODS 60SD rats were given cerebral infraction and24hours later divided into2groups at random:rehabilitation groups were given balancing，grasping，rotating and walking exercises every-day，braking groups were fixed in cages.Immunohis-tochemistry was used to intect the CGRP protein expression respectively24h ......