关键词: 糖尿病;睡眠呼吸暂停综合征;多道睡眠描记术

    摘 要:目的 探讨糖尿病患者的睡眠呼吸紊乱(sleep relat-ed breathing disorders，SRBD)特点及临床意义. 方法 非胰岛素依赖性糖尿病(non-insulin dependent diabetes，NIDDM)23例，睡眠呼吸暂停综合征(sleep apnea syndrome，SAS)13例，PSG结果进行对比研究. 结果 48%的糖尿病(DM)患者合并SRBD;DM合并SRBD者并发高血压及心脑血管病明显增多17%vs73%，P<0.01;DM的SRBD中中枢性呼吸紊乱(CBD)占44.3%，可能为DM患者的PSG特征. 结论 DM易发生SRBD;SAS可能加重糖尿病，系因缺氧产生胰岛素抵抗以及儿茶酚胺分泌增高等所致;CBD可能为PSG诊断DM的一个辅助特征;DM行PSG检查，可早期发现加重病情的SRBD，有利于对糖尿病的防治.

    Relationship between diabetes and sleep related breathing disorders

    LI Hong-Zeng，YOU Guo-Xiong，ZHU Shi-Xiu

    Department of Neurology，Tangdu Hospital，Fourth Military Medical University，Xi'an710038，China

    Keywords:diabetes mellitus;sleep apnea syndromes;polysomnography

    Abstract:AIM To study the relationship between sleep re-lated breathing disorders(SRBD)and diabetes mellitus.METHODS Twenty-three non-insulin dependent diabetes mellitus(NIDDM)patients were analyzed and compared with obstructive sleep apnea syndrome(OSAS)patients by polysomnography(PSG)method.RESULTS Of the DM patients48%were accompanied with SRBD;complication of hypertension and cardio-cerebral vascular diseases increased markedly(17%vs73%P<0.01)in this group;44%of the DM SRBD belonged to the central breathing disorder(CBD).CONCLUSION DM is likely to be complicated ......