关键词: 部队;甲型病毒性肝炎;接种策略;成本-效果分析

    摘 要:目的 筛选出部队人群疫苗预防甲肝的最佳策略，为部队控制甲肝流行提供科学决策的依据. 方法 运用成本-效果分析法和决策学方法. 结果 从接种方案的成本-效果比(CER)来看，对部队干部人群实施先筛选再接种，其CER为-1231.27，直接接种CER为-269.84，新兵先筛选再接种，其CER为-762.56，直接接种CER为-32.10.经灵敏度分析发现，决策结果稳定，不随参数取值的变化而改变. 结论 当前条件下，部队甲肝疫苗接种优选对象为干部人群，并首选先筛选再接种方案，由于新兵接种甲肝疫苗也产生正效益，所以对新兵也应考虑接种.

    Cost┐effectiveness analysis of hepatitis A vaccina┐tion strategy among Chinese PLA

    SU Jing-Kuan，FANG Shen-Ying，ZHANG Zhi-Ying，XU De-Zhong，LI Yuan-Gui

    Department of Epidemiology，Faculty of Preventive Medicine，Fourth Military Medical University，Xi'an710033，China

    Keywords:military;hepatitis A;vaccination strategy;cost-effectiveness analysis

    Abstract:AIM To screen the most cost effective strategy for vaccination against hepatitis A in the armies.METHODS Cost-effectiveness and decision tree analysis were adopted for decision making of vaccination strategies against HA in armies.RESULTS Cost-effectiveness ratio(CER)of‘screen and vaccination'(-1231.27)was lower than that of‘direct vaccination'(-269.84)for the officers.As far as the recruits were concerned，the former(-762.56)was low-er than the latter(-32.10)too.Sensitivity analysis demon-strated that the result of decision did not change with the variation of the input data.CONCLUSION Officers should be considered first for vaccination and the screening-vaccina-tion strategy is most cost-effective for them.The recruits should also be considered for the positive benefit of vaccina-tion. ......