关键词: 急性肝炎;分型诊断;成本效果分析;系统综述

    摘 要:目的 探讨急性病毒性肝炎病原学分型诊断最佳路径. 方法 系统综述、成本效果分析. 结果 根据我国历史文献，用系统综述方法分析我国急性病毒性肝炎构成比，十二条分型路径中以HBV→HAV→HEV→HCV诊断费用最低，13403.44元/千病例，成本效果比(CER)为13.84.其次为HBV→HAV→HCV→HEV，HAV→HBV→HEV→HCV和HAV→HBV→HCV→HEV. 结论 目前我国现行急性病毒性肝炎分型诊断方法(甲、乙、丙、戊型肝炎同时检测)的成本最高，散发季节以HBV→HAV→HEV→HCV的诊断路径最为经济，基本可以完成分型诊断任务，而在甲型肝炎出现爆发时以路径HAV→HBV→HEV→HCV最经济.

    Study on the most effective etiologic diagnosis strat┐egy of acute viral hepatitis in China

    SHAO Zhong-Jun，YAN Yong-Ping，ZHANG Zhi-Ying，XU De-Zhong，WANG Xue-Ping，HUANG Ying

    Department of Epidemiology，Faculty of Preventive Medicine，Fourth Military Medical University，Xi'an710033，China

    Keywords:acute viral hepatitis;etiologic diagnosis;cost-ef-fectiveness analysis

    Abstract:AIM To seek the most effective etiology diagno-sis strategy of acute viral hepatitis.METHODS Systemic review and cost-effectiveness analysis were employed.RE┐SULTS According to domestic historical documents，the systemic review was adopted to analyze the proportion of a-cute viral hepatitis in China，it was demonstrated that hepati-tis A accounted for39.29% ......