【摘要】 目的 观察125I放射微粒植入对前列腺癌的治疗效果。方法 对26例临床确诊为前列腺癌患者经皮穿刺在癌组织植入125I放射微粒，每例平均36粒，术后复查肛诊、B超、影像学及血生化指标。结果 患者植入治疗经过顺利，2例少量出血，留置导尿后愈合，3个月后经肛诊、直肠B超示结节缩小，前列腺特异性抗原(PSA)降低，多普勒超声显示结节内动脉收缩期最大血流速度(VS)、阻力指数(RI)及动脉搏动指数(PI)均明显下降。结论 125I放射微粒植入对前列腺癌的治疗安全性好、效果可靠。

    【关键词】 前列腺癌；放射性核素；放射；碘

    Radioactive granule 125I implantation mild traumatically for prostate cancer

    SHEN Jin-gui,LU Hui-ping, YV Mei, et al.

    Department of Urology, Dahua Hospital, Shanghai 200237, China

    【Abstract】 Objective To evaluate the therapeutic effect of radioactive granule 125I implantation for prostate cancer.Methods Percutaneouslly punctured and implanted radioactive granule 125I into the cancer tissue among 26 cases which were confirmed as prostate cancer clinically, average 36 per case, repeated anal examination, images and blood biochemistry criterions were performed postsurgically. Results The implantation processes were safe, less hemorrhage was seen in 2 cases and disappeared after indwelling catheter. Three months later, the anal examination and B-ultrasound per rectum showed that the prostate nodule dwindled, prostate special antigen(PSA) declined, Doppler ultrasound showed that the arterial systolic blood volume speed(Vs), resistance index(RI) and arterial pulsation index(PI) inside the nodule all declined obviously.Conclusion The radioactive granule 125I implantation was safe and had credible effect for the prostate cancer. ......