【摘要】 目的 观察酒精中毒患者血清尿酸及心肌酶水平的动态变化与心脑血管疾病的相关性。方法 测定酒精中毒患者(52例)入院时血清尿酸、乳酸脱氢酶(LDH)、谷草转氨酶(GOT)、肌酸激酶(CK)水平并行心电图检查，正常人(36例)作为对照组。结果 重度酒精中毒者血清尿酸(568.45±46.35)μmol/L及CK(521.29±48.37)U/L水平较正常人对照组明显升高(P均<0.05)，同时多伴有心电图(ECG)缺血性改变，轻度中毒者变化不明显。结论 重度酒精中毒可引起体内尿酸(UA)及肌酸激酶(CK)水平升高，酒精与尿酸均可增加心脑血管疾病的发病风险。

    【关键词】 酒精中毒；血清尿酸；心肌酶；心脑血管疾病

    The clinical significance of the changes in serum uricacid and myocardial enzymes level of patients with alcoholism

    XU Rui-jia，GUANG Xiao-hong，HU Ai-min.

    Department of Emergency，Air Force General Hospital，Beijing 100036，China

    【Abstract】 Objective To observe changes in uric acid(UA)，lactic dehydrogenase(LDH)，glutamic-oxaloacetic transaminase(GOT)，creatine kinase(CK) of patients with alcoholism and its relation to cardiovascular and cerebral vascular disease.Methods Plasma uric acid ......