芪丹通脉片对大鼠急性心肌缺血损伤的影响
芪丹通脉片,,芪丹通脉片;急性心肌缺血;线粒体;钙,0引言,1材料和方法,2结果,3讨论,【参考文献】
Effects of Qidantongmai tablet on acute myocardial ischemia injury in ratsHANG Li1, MA Jing, WANG ZongRen, YANG XiZhong, MA ShinPin, LI MengMeng, XIAO TieHui, LI JingHua, ZHENG Jin
Department of Traditional Chinese Medicine, Department of Pharmaceutics, Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xian 710033, Chain
【Abstract】 AIM: To study the effects of Qidantongmai tablet (QDTMT) on acute myocardial ischemia in rats. METHODS: Acute myocardial ischemia was induced by subcutaneous injection of isoproterenol (ISP. 5 mg·kg-1) into SD rats. Activities of ATPase and content of Ca2+ were observed in myocardial tissue and mitochondria. The changes of myocardial ultrastructure were examined by transmission electron microscope. RESULTS: Compared with those of the controls, activities of ATPase in mitochondrion were strengthened in QDTMT group [(40.9±8.1)vs(23.1±5.7) ......
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