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芪丹通脉片对大鼠急性心肌缺血损伤的影响
http://www.100md.com 《第四军医大学学报》 2003年第5期
芪丹通脉片,,芪丹通脉片;急性心肌缺血;线粒体;钙,0引言,1材料和方法,2结果,3讨论,【参考文献】
     Effects of Qidantongmai tablet on acute myocardial ischemia injury in rats

    HANG Li1, MA Jing, WANG ZongRen, YANG XiZhong, MA ShinPin, LI MengMeng, XIAO TieHui, LI JingHua, ZHENG Jin

    Department of Traditional Chinese Medicine, Department of Pharmaceutics, Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xian 710033, Chain

    【Abstract】 AIM: To study the effects of Qidantongmai tablet (QDTMT) on acute myocardial ischemia in rats. METHODS: Acute myocardial ischemia was induced by subcutaneous injection of isoproterenol (ISP. 5 mg·kg-1) into SD rats. Activities of ATPase and content of Ca2+ were observed in myocardial tissue and mitochondria. The changes of myocardial ultrastructure were examined by transmission electron microscope. RESULTS: Compared with those of the controls, activities of ATPase in mitochondrion were strengthened in QDTMT group [(40.9±8.1)vs(23.1±5.7) ......

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