【摘要】 目的 测定复方氨林巴比妥注射液中安替比林含量。方法 在硫酸介质中，安替比林与亚硝酸钠相互作用，生成亚硝基安替比林，该溶液的最大吸收波长为345nm。据此建立测定安替比林的方法。结果 线性范围为0～16μg/ml，检出限为0.40μg/ml。结论 该方法应用于复方氨林巴比妥注射液中安替比林含量测定，结果满意。

    【关键词】 紫外分光光度法；安替比林

    【Abstract】 Objective To the determination of the antipyrine in fu fang an lin ba bi tuo injection liquid.Methods A novel and sensitive ultraviolte spectrophometric method for the determination of the antipyrine was developed,which is based on the phenazone-nitrite reaction,producting nitroso-phenazone,in sulphuric acid medium,the antipyrine content was determined photometrically at 345nm.Results The antipyrine in the linear concentration range of 0～16μg/ml was determined with a detection limit of 0.40μg/ml.Conclusion The method has been applied to the determination of the antipyrine in fu fang an lin ba bi tuo injection liquid.The possible reaction mechanism was also discussed.

    【Key words】 ultraviolet spectrophotometry;antipyrine

    安替比林属于吡唑酮类解热镇痛药 ......