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下咽鳞癌不同方案治疗的临床结果分析
http://www.100md.com 邢海杰, 曾宗渊, 陈福进, 郭朱明, 杨安奎,
鳞癌;下咽肿瘤;治疗;预后邢海杰,曾宗渊,陈福进,郭朱明,杨安奎,张诠.下咽鳞癌不同方案治疗的临床结果分析. 世界华人消化杂志2006;14(3)299-305http,www.wjgn
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     邢海杰,曾宗渊, 陈福进, 郭朱明,杨安奎, 张诠, 华南肿瘤学国家重点实验室, 中山大学肿瘤防治中心头颈科 广东省广州市 510060

    通讯作者:曾宗渊, 510060, 广东省广州市东风东路651号, 中山大学肿瘤防治中心头颈科. tjk@gzsums.edu.cn

    电话:020-87343302 传真:020-87331906

    收稿日期:2005-10-14 接受日期: 2005-10-17

    An analysis of outcomes for hypopharyngeal squamous cell carcinoma treated with different methods

    Hai-Jie Xing, Zong-Yuan Zeng, Fu-Jin Chen, Zhu-Ming Guo, An-Kui Yang, Quan Zhang

    Hai-Jie Xing, Zong-Yuan Zeng, Fu-Jin Chen, Zhu-Ming Guo, An-Kui Yang, Quan Zhang, State Key Laboratory of Oncology in Southern China; Department of Head and Neck Surgery, Cancer Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China

    Correspondence to: Dr. Zong-Yuan Zeng, State Key Laboratory of Oncology in Southern China; Department of Head and Neck Surgery, Cancer Center, Sun Yat-sen University, 651 Dongfeng East Road, Guangzhou 510060, Guangdong Province, China. tjk@gzsums.edu.cn

    Received: 2005-10-14 Accepted: 2005-10-17

    Abstract

    AIM: To analyze the outcomes of hypop-haryngeal squamous cell carcinoma treated with different methods and to explore a more effective therapy for it.

    METHODS: This retrospective study concerns 187 hypopharyngeal squamous cell carcinomas and their characteristics. The survival rate, recurrence rate and influence of laryngeal preservation on the survival were compared among different therapies.

    

    RESULTS: The overall 5-year survival rate was 44.9%. The 5-year survival rates of stageⅠ,Ⅱ,Ⅲ and Ⅳ were 100%, 81.8%, 47.6%, and 30.2%, respectively, and the former two were significantly higher than the latter two (c2 = 22.878, P = 0.000 1). The overall 5-year survival rate for synthetic therapy, surgery and radiotherapy alone was 60.8%, 38.7%, and 22.0%, respectively, and the survival rates of patients at stage Ⅲ and Ⅳ were 75.5% and 45.3% for synthetic therapy, 33.3% and 17.6% in surgery alone, 16 ......

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