恶性呼吸道狭窄的介入合并放疗的临床研究
气管,,支架；气管；支气管狭窄；并发症,1资料与方法,2结果,3讨论,【参考文献】
【摘要】 目的 分析介入合并放射治疗晚期恶性肿瘤所致呼吸道狭窄的治疗效果及疗效。方法 30例行呼吸道支架留置的患者，可以接受放射线治疗合并常规外照射。对支架留置的成功率、患者临床症状及呼吸状态的改善情况、治疗前后血气分析、生存率及并发症等进行了评价。结果 支架留置成功率为100%。18例治疗前后的血气分析PaO2从治疗前的(65.3±19.2)mmHg上升到治疗后1周的(79.9±180.9)mmHg(P<0.05)；而PaCO2也从治疗前的(42.1±9.2)mmHg下降到治疗后的(38.2±6.7)mmHg。29例支架留置后的平均生存期为123天。合并放射线治疗的9例的平均生存期为182天，较没有合并放射线治疗的20 例的65天的平均生存期明显延长(P<0.01)。轻度的并发症共发生3例，有支架发生移动、部分破损及支架的变形各1例。结论 金属支架留置可以明显提高生存质量；合并放射线照射治疗可明显延长晚期癌症患者的生存期。【关键词】 支架；气管；支气管狭窄；并发症
The treatment of stent combined with radiotherapy for malignant airway stenosis
XU Xiang-ying,Hiroyuki Tajima,Michihiro Ishioh,et al.
Department of Radiotherapy,Tumour Hospital,Harbin Medical University,Harbin 150040，China
【Abstract】 Objective The purpose of this study is to clarify the clinical usefulness of Z stent combined with radiotherapy for the management of malignant tracheobronchial stenosis.Methods Sixty-nine stents were used in 29 patients.The technical success rates,clinical condition,respiratory status,blood gas analysis,survival rate,and complications were reviewed on the basis of the patients medical records and radiographies.Results All stents were successfully placed in the appropriate position.After the procedure,respiratory status improved in 97%(28/29) of the patients.PaO2 increased statistically (P<0.05),and PaCO2 decreased one week after the treatment.Mean survival of 29 patients after stent placement was 123 days.Mean survival in 9 patients treated in combination with radiotherapy (182days) was statistically longer (P<0.01) than in those treated without radiotherapy (65days).No severe complications were encountered during and after the procedure.Only 3 minor complications were observed.1 stent migration,1 partial rupture of the stent,and 1 stent deformation were observed.Conclusion Stent treatment in combination with radiotherapy is useful for palliation of malignant tracheobronchial stenosis,and would contribute to improve the life quality of patients with advanced cancer. ......
您现在查看是摘要页，全文长 11088 字符。