双脱氧葡萄糖_____18F双脱氧葡萄糖；合成；影响因素

不同浓度H218O等因素对合成18F双脱氧葡萄糖的影响

http://www.100md.com 《第四军医大学学报》 2004年第17期

双脱氧葡萄糖,,18F双脱氧葡萄糖；合成；影响因素,0引言,1材料和方法,2结果,3讨论,【参考文献】

     Effect of H218O concentration and other factors on 18FFDG syntheses

    YUAN MengHui, ZHOU LiangFei, XU HaiFeng, ZHOU RunSuo, ZHOU FeiHua, WU ShaoJun

    1Department of Nuclear Medicine, Tangdu Hospital, Fourth Military Medical University, Xi’an 710038, China, 2EBCO Technologies INC., Canada

    【Abstract】 AIM: To analyze the effects of the concentration of H218O on the synthesis of 218F2deoxyβDglucose (18FFDG) using singlepot acid hydrolysis. METHODS: Different concentration of H218O was used and the synthesis rate in each 18FFDG production was observed. RESULTS: The concentrations of H218O were found to have little effect on the synthesis rate of 18FFDG. The main byproduct was 13N, mostly in gaseous form, and with little involvement in the 18FFDG production. The determinant in the synthesis was the presence of water. Via several dehydration steps, water could be minimized and the production rate would be maximized. CONCLUSION: The concentration of H218O can be set with the number of patients to be examined, thus ensuring the normal synthesis rate and reducing the cost at the same time. ......

百拇医药网 http://www.100md.com/html/DirDu/2006/02/19/87/21/58.htm

您现在查看是摘要页，全文长 10557 字符。