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腔内成型术治疗犬顽固性脑血管痉挛
http://www.100md.com 《第四军医大学学报》 2003年第7期
脑血管痉挛,,脑血管痉挛;血管成形术;动物,0引言,1材料和方法,2结果,3讨论,【参考文献】
     (第四军医大学西京医院: 神经内科, 放射治疗科, 陕西 西安 710033)

    Endovascular therapy for canine refractory cerebral vasospasm in dogs

    HAN JunLiang, WAN Qi, ZHANG XueXin, LI Li, GUO YiChuan, ZHANG Wei

    Department of Neurology, Department of Radiation Therapy, Xijing Hospital, Fourth Military Medical Univercity, Xian 710033, China

    【Abstract】 AIM: To investigate the efficacy of treating experimental refractory cerebral vasospasm (rCVS) with percutaneous tansluminal angioplasty (PTA) or intraartery papaverine infusion (IAP) plus PTA. METHODS: 45 adult mongrel dogs were sacrificed and 40 were used in experimental group and 5 in the control. Artery spasm was induced by twotime blood injection into brain cisterns. In the experiment group, PTA or IAP plus PTA was chosen by the status of vessels. In the control group, papaverine was given through intraveins. RESULTS: Basilar arteries of all the dogs were constricted after the twotime blood injection. In the experimental group, 20 dogs were treated by PTA but only 18 succeeded. 13 dogs in the experimental group were treated by IAP plus PTA therapy, but only 3 of them succeeded. In the control group, the spastic arteries of all dogs showed no improvement following the therapy. When reexamined 20 days later, the 21 canines treated by either PTA or IAP plus PTA all had normal angiograph, while those of the control group and those who had not successfully had PTA or IAP plus PTA in experiment group had little change. CONCLUSION: PTA is effective treatment of cerebral vasospasm. ......

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