Effects of ultraviolet irradiation on function of lymphocyte in banked blood

    WANG Baoª²Yan, ZHANG Jianª²Geng, LIU Shuª²Hui, ZHU Hongª²Mei, WANG Baoª²Ping, WEI Shengª²Lu

    1Department of Blood Transfusion, First Hospital£¬Xi¬ðan Jiaotong University, Xi¬ðan 710061, China, 2Blood Center of Shaanxi Province, Xi¬ðan 710061, China

    ¡¾Abstract¡¿ AIM: To explore the effects of ultraviolet irradiation on the function of lymphocytes in banked blood. METHODS: Changes of lymphocyte subgroups, lymphocyte activity, lymphocyte transformation, interleukinª²2 and its receptor were tested before and after ultraviolet irradiation, and after storage for 72 h separately. RESULTS: Ultraviolet irradiation inhibited the lymphocyte activity. As compared with that of the control group, the content of interleukinª²2 decreased significantly with prolonged storage time(P<0.05). Ultraviolet irradiation markedly inhibited the lymphocytes transformation(P<0.01). CD3+, CD4+ and CD8+ lymphocyte subgroups in banked blood decreased as compared with those of prestorage in the two groups ......