Prevention and treatment of fungal infection in the living┐related small bowel transplantation

    ZHANG Hong-Wei WANG Wei-Zhong LING Rui SONG Wei-Liang WU Guo-Sheng LI Meng-Bin LI Ji-Peng

    Keywords:small bowel;organ transplantation;living relat-ed;fungus

    Abstract:AIM To make a retrospective analysis of the ef-fective methods for prevention and treatment of fungal infec-tion in the living-related small bowel transplantation(LSBT).METHODS Two LSBTs have been performed successfully on2patients with short gut syndrome in our hospital since1999.Immunosuppressive agents including tacrolimus(FK506)，mycophenolate mofetil(MMF)and methylprednisolone were used for immunosuppression after the transplants.The measures for prevention and treatment of fungal infection included pre-transplant intensive prepara-tion，continuous post-transplant fungal monitoring and intra-venous allitridi(30mg to60mg per day)followed by oral fluconazole capsules(50mg per day).RESULTS Both the recipients suffered one episode of acute rejection and contract-ed candida infection.The local fungal infection，viz.candida ......