关键词: 血小板输注;血液病;再生障碍性贫血;白血病

    摘 要:目的 探讨出血性血液病患者血小板输注效果及影响因素. 方法 79例血液病患者(急性白血病53例，再生障碍性贫血26例)，输注单采或多人份混合血小板悬液，1h和24h后检测外周血小板计数，以校正血小板计数增值(CCI)判定输注效果并讨论其影响因素. 结果 ①单采组CCI显著高于混合组(1h P<0.05，24h P<0.01);②87.3%出血症状改善或消失;③急白感染组无效输注率为50.0%，非感染组18.5%(P<0.01);④急性白血病(AL)组无效输注率15.1%，再生障碍性贫血(AA)组46.2%. 结论 血小板输注是治疗因血小板减少导致出血的有效措施，感染影响输注效果，再障组无效输注率高于急性白血病组.

    Efficiency of platelet transfusion in patients with hematologic diseases

    GUO Qing-Dong DAI Yue-E MU Shi-Jie FU Ju-Fang ZHANG Xian-Qing XIA Ai-Jun ZHENG Yan

    1 Institute of Neurosurgery of Chinese PLA，

    2 Department of Transfusion，

    3 Department of Hema-tology，Xijing Hospital，Fourth Military Medical University，Xi'an710033，China

    Keywords:platelet transfusion;blood diseases;anemia，aplastic;leukemia

    Abstract:AIM To investigate the effect of platelet transfu-sion in patients with hematologic diseases and the influence factors.METHODS The apheresis platelets(AP)and platelet-rich-plasmas(PRP)were transfused to79patients(acute leukemia ......