图像重建联合立体定向放射治疗肺癌36例
肺肿瘤,,肺肿瘤;,图像处理,计算机辅助;立体定位技术;放射疗法,0引言,2结果,3讨论,【参考文献】
Image reconstruction and stereotactic radiotherapy for 36 patients with lung carcinomaFAN FengYun, ZHANG BingFang, LU Jun, WEI WenSheng, SHI Mei,NAN KeJun
1Department of Radiotherapy, 2Department of Respiratory Medicine,Xijing Hospital, Fourth Military Medical University, Xian 710033, China, 3Department of Oncology,First Hospital,Xian Jiaotong University,Xian 710061,China
【Abstract】AIM: To discuss the clinical effects of image reconstruction and stereotactic radiotherapy in the management of lung carcinoma. METHODS: Included in this study were 36 patients with lung carcinoma. After the lesions were localized by CT scans with 2 mm slice thickness, the images were reconstructed and the clinical tumor volume (CTV), planning tumor volume (PTV) and dose-volume histograms of the involved lung were calculated. By using Leibinger stereotactic radiotherapy planning system and Varian Clinic 600 c or 2300 EX, a series of 5~8 fractions of radiotherapy was conducted once daily with 5~7 Gy per fraction. RESULTS: None of the 36 patients died during the treatment. The general conditions of the patients were assessed by means of Karnofsky performance status (KPS). Preradiotherapy KPS scores were 50~90 (mean 67.2), while the postradiotherapy KPS scores were 60~100 (mean 79.4). Follow-up(6-36 months)found 6 cases of complete remission, 23 cases of partial remission, 3 cases of no change and 4 progressed, with control rate being 80.6%. CONCLUSION: Image reconstruction and stereotaxis radiotherapy has excellent short-term curative effects in the treatment of lung carcinoma. ......
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