[摘 要] 目的 探讨肝癌病人肝移植术中血液酸碱平衡及电解质浓度变化的规律，为肝癌病人行肝移植术时针对血液酸碱及电解质紊乱治疗提供参考依据。 方法 系统回顾分析16例因肝癌行肝移植术病人术中血液钾、钠、钙离子浓度和pH、HCO-3 、BE值的变化规律。 结果 血K+ 从无肝期开始下降;开放后即刻呈现一过性升高表现，部分病人表现为暴发性高血钾。血游离钙在无肝期和新肝期降低明显。无肝期和新肝期pH、HCO-3 、BE值的变化表现为代谢性酸中毒。 结论 手术开始后，从无肝期就应注意纠正低血钾和低血钙，开放瞬间注意暴发性高血钾。保持血液动力学的稳定，同时进行过度通气和给予适当的碱性物质有助于减轻酸性物质的产生和酸中毒。

    [关键词] 肝移植;电解质;酸碱平衡;肝癌

    Changes of plasma electrolyte concentrations and blood gasses during liver transplantation in hepatic cancer patients

    WANG Song-bai，CUI Guang-shan，SUN Jia-tan，LI Hai，LIU Jun-tang，LEI Zhi-li

    (Department of Anesthesiology，No.251Hospital of PLA，Zhangjiakou075000，China)

    Abstract:Objective To investigate the changes of plasma electrolyte concentrations and blood gasses during orthotopic liver transplantation in hepatic cancer patients.Methods The data of16patients undergoing orthotopic liver transplantation for hepatic cancer were collected and analyzed retrospectively.Arterial blood samples were harvested before anesthesia induction ......