(汕头大学医学院第二附属医院外科， 广东 汕头 515041)

    摘 要:目的:探讨采用平阳霉素行小儿体表血管瘤注射的临床疗效及安全性。方法:将平阳霉素配为1%浓度，用带第4号针头注射器吸取适量药液，根据血管瘤大小直接注射至瘤体内，直至瘤体表面发白肿胀为止。每1~2周注射一次，每次量不超过6mg。结果:182例患者经平阳霉素注射治疗后，随访3个月到1年。治愈率49.5%、显效率38.5%、总有效率88%。除部分患儿注射局部肿痛外，全身不良反应轻微。结论:平阳霉素瘤体内注射治疗小儿体表血管瘤疗效确切，副作用小、安全可靠。

    关键词: 平阳霉素; 血管瘤; 注射治疗

    Clinical Study of Intratumoral Pingyangmycin Injection for Hemangiomas in Children

    ZHENG Jun-hong, LI Lin-fen, LIN Jing-xia, et al

    ( The 2nd Affiliated Hospital to Shantou Univ. Medical College, Guangdong Shantou 515041, China)

    Abstract:Objectives: To observe the efficacy of pinyanmycin injection for superficial hemangiomas in children. Methods: Pingyangmycin was intratumorally injected to the hemangioma mass at the concentration of 1% until the mass had become pale and swollen once two weeks for 3～5 times. Results: 182 children received pingyangmycin injection and were followed for 3 months to 1 year. The cure rate was was 49.5%, and the effectiveness rate was 38.5%. Therefore, the total effectiveness rate was 88%. The complication was minimal. Conclusions: Intratumoral injection of pingyangmycin was a safe, convenient and effective therapeutic modality for superficial hemangioma in children. ......