胃痛立应软胶囊制备中二氧化碳超临界流体萃取后的提取工艺研究
胃痛立应软胶囊,,胃痛立应软胶囊;提取工艺;高良姜素,1材料,2方法与结果,3讨论,参考文献:
摘要:目的:研究胃痛立应软胶囊制备中二氧化碳超临界流体(SFECO2)萃取后药材的提取工艺。方法:对比乙醇回流、温浸、超声及水煎等提取工艺,以溶媒浓度、用量、提取时间为研究因素,经正交设计进行提取工艺条件的优选。结果:最佳提取工艺路线为10倍量75%乙醇回流提取1次,提取时间为1.5 h。结论:以高良姜素提取率为指标,该最佳提取工艺能充分提取药材中的有效成分。关键词:胃痛立应软胶囊;提取工艺;高良姜素
Study on Extraction in the Processes of Weitongliying Soft Capsule after Extracted by Supercritical Carbon Dioxide Fluid
FU Haizhen,JIA Xiaobin,YANG Zhonglin,XIA Guohua,XIN Huaisheng
(1.School of Pharmacy,Jiangsu University,Zhenjiang,212001;China; 2.Academy of TCM of Jiangsu, Nanjing 210028;China; 3.School of Traditional Chinese Medicines,China Pharmaceutical University,Nanjing 210038,China)
Abstract:Objective:To study the extraction in the processes of Weitongliying Soft Capsule after extracted by Supercritical carbon dioxide fluid.Methods:The most appropriate technology was screened based on the comparative study among the technology of ethanol circumfluence,ultrasonic extraction,water warm immersion and water decoction ......
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