子宫内膜异位症sICAM1和sHLAⅠ变化及意义
子宫内膜异位症,,子宫内膜异位症;HLA抗原;胞间粘附分子1;酶联免疫吸附测定,0引言,1对象和方法,2结果,3讨论,【参考文献】
Changes of sICAM1 and sHLAⅠin endometriosis and its significanceZHANG Rong, LUO RuoYu
Department of Gynecology and Obstetrics, Peoples Hospital, Wuhan University, Wuhan 430060, China
【Abstract】 AIM: To investigate the relationship between endometriosis (EMs) and the levels of soluble intercellular adhesion molecule1 (sICAM1) and soluble human leucocyte antigen1 (sHLAⅠ). METHODS: Thirty serum and 30 peritoneal fluid (PF) of patients with EMs (test group) and 30 serum and 30 peritoneal fluid of patients without EMs (control group) were studied. The levels of sICAM1 and sHLAⅠwere detected by enzymelinked immunosorbent assay (ELISA). RESULTS: ① Significantly higher levels of sICAM1 in serum and PF were observed in patients with EMs compared with those in controls (P﹤0.05). ② The levels of sICAM1 in serum and PF were significantly different and the levels in earlystage EMs group were higher than those in advanced group (P﹤0.05). ③ Serum sHLAⅠ cevel was lower in EMs group (P﹤0.05) but the level in earlystage EMs group was higher than that in advanced group (P﹤0.05). ④ There were no statistically significant differences in the levels of sHLAⅠin PF between the patients and the controls (P﹥0.05). CONCLUSION: Changes of sICAM1and sHLAⅠmay play a role in the genesis of endometriosis. ......
您现在查看是摘要页,全文长 7192 字符。